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Table 1 Treatment sequences (A = amitriptyline, P = pregabalin, D = duloxetine)

From: Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial

 

Treatment pathway 1

Treatment pathway 2

Treatment pathway 3

Sequence 1

A-P

D-P

P-A

Sequence 2

A-P

P-A

D-P

Sequence 3

D-P

A-P

P-A

Sequence 4

D-P

P-A

A-P

Sequence 5

P-A

A-P

D-P

Sequence 6

P-A

D-P

A-P

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Trials

ISSN: 1745-6215