A novel hand-assisted laparoscopic versus conventional laparoscopic right hemicolectomy for right colon cancer: study protocol for a randomized controlled trial

Table 1 Perioperative outcome parameters and schedule of study visits and follow-up

Measures	Preoperative	Intraoperative	Daily in-hospital study visit					Follow-up
Measures	Preoperative	Intraoperative	POD 1	POD 2	POD 3	POD 4	POD 5	M1	M3	M6	M9	M12	M15	M18	M21	M24	M27	M30	M33	M36
Minimally invasive evaluation		X
Quality of specimens		X
VAS score			X		X		X
Inflammatory parameters	X		X		X		X
Short-term recovery			X	X	X	X	X
Physcial examination	X							X	X	X	X	X	X	X	X	X		X		X
Tumor marker	X							X	X	X	X	X	X	X	X	X		X		X
Abdominal and pelvic CT scan	X									X		X		X		X		X		X
Colonoscopy	X											X				X				X
Adverse event		X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X

Preoperative study visits will be scheduled within 7 days before surgery
Minimally invasive evaluation includes operation time, blood loss, intraoperative complication, and incision length
Inflammatory parameters including procalcitonin (PCT), C-reactive protein (CRP), and interleukin (IL)-6 will be measured at 24 h, 72 h, and 120 h postoperatively
Short-term recovery including time to first flatus, liquid diet, and duration of hospital stay will be recorded daily in-hospital
Colonoscopy will be performed at 1 year after surgery and will be repeated at 3 years if no lesions are found
Tumor marker includes carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9)
CT computed tomography, M Month, POD postoperative day, VAS visual analogue scale

ISSN: 1745-6215