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Table 1 Parameters measured at the distinct time points

From: The impact of phosphate-balanced crystalloid infusion on acid-base homeostasis (PALANCE study): study protocol for a randomized controlled trial

Measurement

Time point

Haemodynamic values

 Norepinephrine dose (mg/h)

T1–T5

 Heart rate (min-1)

T1–T5

 Systolic blood pressure (mmHg)

T1–T5

 Diastolic blood pressure (mmHg)

T1–T5

 Central venous pressure (mmHg)

T1–T5

 Stroke volume variation (%)

T1–T5

 Cardiac output (ml/min)

T1–T5

 Blood loss (ml)

T1–T5

 Haemoglobin (g/dl)

T1–T5

 Haematocrit (%)

T1–T5

 Urine volume (ml)

T1–T5

 Crystalloid administered (ml)

T1–T5

Serum electrolytes

 [PO4 3-] ionized (mmol/l)

T0–T5

 [PO4 3-] (mg/dl)

T0–T5

 [Na+] (mmol/l)

T1–T5

 [K+] (mmol/l)

T1–T5

 [Cl] (mmol/l)

T1–T5

 [Mg2+] (mmol/l)

T1–T5

 [Ca2+] (mmol/l)

T1–T5

 Osmolality (mosmol/l)

T1–T5

Renal function

 Serum creatinine (mg/dl)

T0 and T6

 Serum urea nitrogen (mg/dl)

T0 and T6

 GFR calculated (ml/min)

T0 and T6

Acid-base values

 Anion gap (mmol/l)

T1–T5

 HCO3- (mmol/l)

T1–T5

 BE (mmol/l)

T1–T5

 pH

T1–T5

 PaCO2 (mmHg)

T1–T5

Stewart acid-base parameters

 [A-] (mmol/l)

T1–T5

 Strong Ion Difference (mmol/l)

T1–T5

 Effective Strong Ion Difference

T1–T5

 Strong Ion Gap (mmol/l)

T1–T5

 Albumin (mg/dl)

T1–T5

 Lactate (mmol/l)

T1–T5

Urine

 [Urinary Na+] (mmol/l)

T1 and T5

 [Urinary K+] (mmol/l)

T1 and T5

 [Urinary Cl] (mmol/l)

T1 and T5

 [Urinary Mg2+] (mmol/l)

T1 and T5

 [Urinary Ca2+] (mmol/l)

T1 and T5

 [Urine osmolality] (mosmol/l)

T1 and T5

 [Urinary phosphate] (mmol/l)

T1 and T5

Glycocalyx components

 Syndecan-1

T1–T5

 Hyaluronic acid

T1–T5

  1. BE base excess, GFR glomerular filtration rate