Skip to main content

Table 1 Inclusion and exclusion criteria

From: The impact of torasemide on haemodynamic and neurohormonal stress, and cardiac remodelling in heart failure – TORNADO: a study protocol for a randomized controlled trial

Inclusion criteria:

 Signed informed consent form

 Age ≥18 years

 Patients with chronic heart failure, as defined by the European Society of Cardiology (update 2016)

 New York Heart Association (NYHA) functional class II–IV

 Patients who require diuretic therapy for maintain euvolaemia

 Stable clinical condition during index hospitalization with established proper diuretic dosage

Exclusion criteria:

 Acute coronary syndrome

 Hypertrophic cardiomyopathy

 Uncontrolled hypertension

 Uncontrolled diabetes

 Serum potassium >6.0 mmol/l

 Serum creatinine >2.5 mg/dl

 Malignancy

 Life expectancy <1 year

 Planned valve surgery or heart transplantation