Fig. 1

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) figure for the schedule of enrolment, interventions and assessments. Time points: t0: baseline; t1: 2 weeks post treatment; t2: 3-week follow-up (FU1); t3: 6- and 12-month follow-ups (FU2); t4: 12-month follow-up (FU3). Abbreviations: FITonICU, Fitness and mobility training in patients with Intensive Care Unit-acquired muscle weakness; FU follow-up; T time point; FAC Functional Ambulation Categories; FSS-ICU Functional Status Score for the Intensive Care Unit Scored; STS ability to stand up from a chair independently; MRC sum score Medical Research Council (sum score of muscle strength of the upper (shoulder, elbow and wrist) and the lower limb (hip, knee and ankle)); PFIT-S Physical Function for the Intensive Care Unit Test-Scored; EQ-5D EuroQol 5 Dimensions questionnaire; RNL-Index Reintegration to Normal Living Index