Table 2 Exclusion criteria by race/ethnic group at the time of the prescreen and clinic screening visit in the LIFT Diabetes trial
Total screened (N = 801) | African Americans (N = 459) | Other race/ethnic groups (N = 342) | P value | |
|---|---|---|---|---|
Non-diabetic | 15 (1.9 %) | 5 (1.1 %) | 10 (2.9 %) | 0.07 |
Under 25 and always on insulin | 7 (0.9 %) | 7 (1.5 %) | 0 (0 %) | 0.02 |
BMI <25 kg/m2 or <27 kg/m2 for insulin users | 71 (8.9 %) | 42 (9.2 %) | 29 (8.5 %) | 0.80 |
History of CVD or cardiovascular procedure* | 132 (16.5 %) | 70 (15.3 %) | 62 (18.1 %) | 0.29 |
Alcohol (>14 drinks for men aged 65 years or less, > 7 drinks for men and women aged over 65 years) or drug abuse | 11 (1.4 %) | 2 (0.4 %) | 9 (2.6 %) | 0.01 |
Other medical conditions (including chronic disease, leg amputation, blood clot, IBD, Crohn’s disease, acromegaly) | 43 (5.4 %) | 31 (6.8 %) | 12 (3.5 %) | 0.06 |
Prior weight loss surgery | 19 (2.4 %) | 12 (2.6 %) | 7 (2 %) | 0.65 |
History of cancer | 4 (0.5 %) | 2 (0.4 %) | 2 (0.6 %) | 1.00 |
Unable to exercise | 43 (5.4 %) | 29 (6.3 %) | 14 (4.1 %) | 0.21 |
Use of steroid pills or shots | 33 (4.1 %) | 18 (3.9 %) | 15 (4.4 %) | 0.86 |
Unwilling to stop weight loss medications/program | 13 (1.6 %) | 6 (1.3 %) | 7 (2 %) | 0.42 |
Pregnancy, breastfeeding | 6 (0.7 %) | 5 (1.1 %) | 1 (0.3 %) | 0.25 |
Hospitalized depression/PHQ-9 | 11 (1.4 %) | 3 (0.7 %) | 8 (2.3 %) | 0.06 |
Physician review includes PAR-Q | 53 (6.6 %) | 31 (6.8 %) | 22 (6.4 %) | 0.89 |
Blood pressure ≥160/100 mmHg | 8 (1.0 %) | 5 (1.1 %) | 3 (0.9 %) | 1.00 |
HbA1c ≥11 % | 42 (5.2 %) | 25 (5.4 %) | 17 (5 %) | 0.87 |
Laboratory exclusions (GFR <45, triglycerides >600) | 10 (1.2 %) | 3 (0.7 %) | 7 (2 %) | 0.11 |
Other reasons (household member works for LIFT, cannot commit to travel, another research study, schedule conflict, no PCP, needs sign language interpreter, ineligible with no reason given) | 109 (13.6 %) | 59 (12.9 %) | 50 (14.6 %) | 0.47 |
Decided not to participate/no show | 171 (21.3 %) | 104 (22.7 %) | 67 (19.6 %) | 0.34 |