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Table 4 Commonly reported adverse reactions of sirolimus therapy (occurring in more than 10% of patients)

From: Pulsed oral sirolimus in advanced autosomal-dominant polycystic kidney disease (Vienna RAP Study): study protocol for a randomized controlled trial

Abdominal pain
Acne
Anemia
Aphthae
Arthralgia
Constipation
Diarrhea
Headache
Hypercholesterolemia
Hyperglycemia
Hypertension
Hypertriglyceridemia
Hypokalemia
Hypophosphatemia
Impaired wound healing
Increased serum creatinine
Increased serum lactate dehydrogenase
Nausea
Pain
Peripheral edema
Pneumonitis
Pyrexia
Stomatitis
Thrombocytopenia
Urinary tract infection