Figure 3
From: Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials
Example of magnetic resonance imaging based selection for thrombolysis. (a) Magnetic resonance angiography demonstrates right middle cerebral artery occlusion (arrow). (b) Two representative perfusion weighted imaging slices demonstrate delayed relative mean transit time in the entire right middle cerebral artery (MCA) territory. (c) Two corresponding diffusion weighted imaging slices demonstrate parenchymal injury only in the deeper parts of the right MCA territory (arrows), a diffusion-perfusion mismatch. Following tissue-type plasminogen activation (tPA) therapy, recanalization of the right MCA is seen (d), with normalization of perfusion (e), and limitation of the parenchymal damage (f).