Figure 7
From: Meta-analysis of randomized phase II trials to inform subsequent phase III decisions
Posterior distributions for treatment effect (log(OR)) in a new trial for ICH assuming a skeptical and vague prior distribution for log(OR). Vague prior distribution (θ ~ N(0,10002)) and skeptical prior distribution (θ ~ N(0,33.33)) for the log OR. The area under the curve (AUC) that is less than zero is the probability that bolus therapy will truly be effective in a new trial. ICH intracranial hemorrhage; AUC area under the curve.