Table 2 Individual and Pharmacy Level Variables Available for Multivariable Analysis
Variable | Description | Database Source |
|---|---|---|
Individual Level | Â | Â |
Sex | Sex of subject | Insurance registry |
Age | Age of subject at index date (calculated using date of birth) | Insurance registry |
Income security benefits | Patient receives income security benefit (a proxy for socioeconomic status) | Prescription drug |
Concurrent medications | Concurrent medications use during one year prior to subject's index date, and for the first 6 months of the study observation period. | Prescription Drug |
|  |    Beta blockers |  |
|  |    Angiotensin converting enzyme inhibitors |  |
|  |    ASA |  |
|  |    Oral hypoglycemics |  |
Prior cardiovascular event | Cardiovascular event(s) in one year prior to subject's index date (Based in ICD-10-CA classifications) | Hospital Services |
|  |    Myocardial infarction (I21. - I23.) |  |
|  |    Stroke (all causes) (I60. - I64.) |  |
|  |    Transient ischemic attack (G45.0) |  |
|  |    Unstable angina (I20.0) |  |
|  |    Other ischemic heart disease (I24. - I25.) |  |
|  |    Revascularization procedures |  |
| Â | PTCA (1.IJ.50, 1.IJ.57.GQ, 1.IL.35), CABG (1.IJ.76) | Â |
|  |    Coronary Angiography (3.IP.10) |  |
Study cardiovascular event | Cardiovascular event(s) during study period (Based in ICD-10-CA classifications) | Hospital Services |
|  |    Myocardial infarction (I21. - I23.) |  |
|  |    Stroke (all causes) (I60. - I64.) |  |
|  |    Transient ischemic attack (G45.0) |  |
|  |    Unstable angina (I20.0) |  |
|  |    Other ischemic heart disease (I24. - I25.) |  |
|  |    Revascularization procedures |  |
| Â | PTCA (1.IJ.50, 1.IJ.57.GQ, 1.IL.35), CABG (1.IJ.76) | Â |
|  |    Coronary Angiography (3.IP.10) |  |
Chronic disease score | Chronic disease score (measure of chronic disease status derived from population-based automated pharmacy data) [37] | Prescription Drug |
Prior hospitalizations | Number of hospitalizations in one year prior to subject's index date | Hospital Services |
Study hospitalizations | Number of hospitalizations during study observation period | Hospital Services |
Physician visits | Number of physician visits during and prior to observation | Physician Services |
Pharmacy Level | Â | Â |
Pharmacy Type | Indicates the type of pharmacy (mass merchandise, chain/grocery, independent) [38] | Investigators to categorize |
Pharmacy Location | Rural (population < 10,000) | Investigators to categorize |
| Â | Regional (population 10,000 - 100,000) | Â |
| Â | Urban (population > 100,000) | Â |
Prescription Volume | Mean number of new statin prescriptions filled monthly (proxy measure for prescription volume) | Prescription Drug |
Pharmacist Coverage | Pharmacist overlap or single pharmacist | Pharmacy survey |
Technician Support | Pharmacy technician support | Pharmacy survey |