From: Intravenous fluid restriction after major abdominal surgery: a randomized blinded clinical trial
Restricted (n = 30) | Standard (n = 32) | Absolute Risk Reduction (95% confidence interval) | |
---|---|---|---|
Postoperative hospital stay (days), mean (SD) | 12.3 (12.7) | 8.3 (4.5) | |
Median (IQR) | 9.0 (6.8–11.3) | 7.0 (6.0–9.8) | 0.049* |
SECONDARY ENDPOINTS | |||
Postoperative complications | 23 | 13 | 0.360 (0.133 to 0.588) |
- Major complications | 12 | 5 | 0.244 (0.028 to 0.460) |
- Death | 1 | 0 | |
- Cardiac | 2 | 0 | |
- Leakage of anastomosis | 6 | 1 | 0.135 (-0.011 to 0.282) |
- Re-admission | 3 | 4 | |
- Minor complications | 11 | 8 | 0.117 (-0.112 to 0.345) |
- Wound infection | 5 | 1 | |
- Wound dehiscence | 1 | 0 | |
- Infection | 0 | 1 | |
- Respiratory | 1 | 0 | |
- Bleeding | 1 | 3 | |
- Thromboembolism | 1 | 0 | |
- Miscellaneous | 2 | 3 | |
Gastric function | |||
- First flatus (days) | 2.8 (1.3) | 2.9 (1.5) | |
Median (IQR) | 3 (2–3) | 3 (1–4) | 0.713* |
- First defecation (days) | 3.7 (1.3) | 3.5 (1.7) | |
Median (IQR) | 4 (3–4) | 4 (2–5) | 0.725* |
- Removal nasogastric tube (days) | 2.3 (1.3) | 2.4 (2.9) | |
Median (IQR) | 2 (1–3) | 2 (1–2) | 0.393* |
- Removal of epidural catheter (days) | 3.3 (1.5) | 3.7 (1.5) | |
Median (IQR) | 4 (2–4) | 4 (3–4) | 0.420* |
- Removal of IV catheter (days) | 4.9 (2.7) | 5.1 (4.5) | |
Median (IQR) | 4 (3–5) | 4 (3–5) | 0.648* |
- Normal diet (days) | 4.3 (1.9) | 4.2 (3.2) | |
Median (IQR) | 4 (3–5) | 4 (3–4) | 0.254* |