Table 2 Characteristics of included categorised trials
Acronym | Full title | Funder | Funding start – end (month/year) | Follow-up duration | Sample size | Trial received from |
|---|---|---|---|---|---|---|
ActWELL | A randomised controlled trial to assess the impact of a lifestyle intervention (ActWELL) in women invited to NHS breast screening | The Scottish Government | Jan 2017 – Dec 2019 | 12 months | 414 | University of Dundee |
AMBER | Abdominal massage for neurogenic bowel dysfunction in people with multiple sclerosis | National Institute for Health Research - Health Technology Assessment (NIHR-HTA) programme | July 2014 – June 2017 | 6 months | 200 | NMAHP Research Unit, Glasgow Caledonian University |
CONFIDeNT | CONtrol of Faecal Incontinence using Distal NeuromodulaTion | NIHR-HTA | Feb 2012 – Apr 2014 | 14 weeks | 212 | Queen Mary University London |
EAGLE | Whether removal of the lens of the eye (lens extraction) for newly diagnosed primary angle closure glaucoma results in better patient-reported health vision, lower intraocular pressure and other outcomes compared with standard management | NIHR - Efficacy and Mechanism Evaluation (NIHR-EME) | Nov 2008 – July 2015 | 3 years | 419 | CHaRT, University of Aberdeen |
ECLS | Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT-Lung test | Chief Scientist Office, Scottish Government and Oncimmune Ltd | Aug 2013 – Aug 2018 | 24 months | 12,000 | University of Dundee |
EMPiRE | AntiEpileptic drug Monitoring in PREgnancy: an evaluation of effectiveness, cost-effectiveness and acceptability of monitoring strategies | NIHR-HTA | Sept 2011 – Apr 2016 | 21 weeks approx. | 1000 | Queen Mary University London |
Acronym | Full title | Funder | Funding start – end (month/year) | Follow-up duration | Sample size | Trial received from |
HEALTH | A multicentre randomised controlled trial comparing laparoscopic supra-cervical hysterectomy with second generation endometrial ablation for the treatment of heavy menstrual bleeding | NIHR-HTA | Jan 2014 – Sep 2018 | 15 months | 648 | CHaRT, University of Aberdeen |
HIP | Management of Hypotension In the Preterm: a multicentre, randomised controlled trial of hypotension management in the extremely low gestational age newborn | European Commission within the 7th Framework Programme | Oct 2010 – Sep 2017 | 2 years | 340 | INFANT Centre, Cork, Ireland |
iQuaD | A multicentre randomised controlled trial comparing oral hygiene advice and periodontal instrumentation for the prevention and management of periodontal disease in dentate adults attending dental primary care | NIHR-HTA | Apr 2011 – Dec 2016 | 36 months | 1860 | University of Dundee & CHaRT, University of Aberdeen |
KANECTa | The use of ketamine as an anaesthetic during electroconvulsive therapy (ECT) for depression: does it improve treatment outcome? | Chief Scientist Office - Scottish Government Health Directorate | Apr 2011 – Apr 2014 | 1 month | 40 | CHaRT, University of Aberdeen |
KAT | Knee Arthroplasty Trial | NIHR-HTA | Dec 1998 – June 2023 | 10–15 years | 2450 | CHaRT, University of Aberdeen |
PIMS | A randomised controlled trial comparing face-down and face-forward positioning after eye surgery for macular holes to see if this improves the rate of macular hole closure | NIHR-HTA | Apr 2015 – Apr 2018 | 3 months | 192 | Queen Mary University London |
SALVO | A Randomised Controlled Trial of Intra-Operative Cell Salvage during Caesarean Section in Women at Risk of Haemorrhage | NIHR-HTA | Oct 2012 – Oct 2016 | Until discharge | 3050 | Queen Mary University London |
Acronym | Full Title | Funder | Funding start – end (Month/Year) | Follow-up Duration | Sample Size | Trial Received From |
SUSPENDa | Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre placebo controlled randomised trial of a calcium channel blocker (nifedipine) and an α-blocker (tamsulosin) | NIHR-HTA | Jun 2010 – Oct 2014 | 12 weeks | 1200 | CHaRT, University of Aberdeen |
TAGS | Treatment of Advanced Glaucoma Study (TAGS): a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma | NIHR-HTA | Jan 2014 – Jan 2020 a(LTFU - Dec 2023 not included) | 2 years | 440 | CHaRT, University of Aberdeen |
TWICSa | A randomised, double-blind placebo controlled trial of the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease | NIHR-HTA | July 2013 – Dec 2017 | 12 months | 1424 | CHaRT, University of Aberdeen |
ViDiFlu | Cluster-randomised, double-blind, placebo-controlled trial of vitamin D supplementation for the prevention of influenza and other respiratory infections | NIHR - Programme Grants for Applied Research | Mar 2010 – Apr 2013 (LTP) | 12 months | 108 units, - approx. 3 participants per unit | Queen Mary University London |
VUE | Two parallel randomised controlled trials of surgical options for upper compartment (vault or uterine) pelvic organ prolapse | NIHR-HTA | Nov 2012 – Jan 2018 | 12 months | 800 | CHaRT, University of Aberdeen |