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Table 2 Calculation of GDS

From: Whole brain radiotherapy (WBRT) after local treatment of brain metastases in melanoma patients: Statistical Analysis Plan

Cognitive domain

Test and output

Calculation

Memory

Hopkins Verbal Learning Test:

A) Total Recall

B) Delayed Rrecall

C) Delayed Recognition

1 = (A + B + C)/3

Verbal fluency

Controlled Oral Word Association:

A) Total Letter Fluency

B) Category Fluency

C) Written Fluency

2 = (A + B + C)/3

Information processing

Trail Making Test A

3

Attention

Digit Span total score

4

Executive function

Trail Making Test B

5

Stroop Color and Word:

6 = (A + B + C + D)/4

 A) Stroop Color

 

 B) Stroop Word

 

 C) Stroop Color-Word

 

 D) Stroop Interference

7 = (5 + 6)/2

Total GDS

 

8 = (1 + 2 + 3 + 4 + 7)/5