Skip to main content

Table 2 Herb addition based on traditional Chinese medicine syndrome differentiation

From: Traditional Chinese medicine versus regular therapy in Henoch-Schönlein purpura nephritis in children: study protocol for a randomized controlled trial

Yin deficiency complicated with blood stasis

Add Chinese herbs as Qingrezhixue granules: Rhizoma anemarrhenae, Cortex phellodendri, Rhizoma polygonati

Main symptoms of yin deficiency

Red tongue with less or no moss and a dark red throat, a low-grade fever with night sweat, sparse purpura

Secondary symptoms of yin deficiency

Feverishness in the palms and soles, dry mouth with thirst, a weak and rapid pulse

Symptoms of blood stasis

Dark purple tongue or bruises on tongue body; varicose veins or blood stasis in sublingual veins; fixed pain or intense pain causing an aversion to touch; thrombogenesis; dark or blue color (cyanosis) in the face, mouth, or gums, around the eyes, or in the lips and extremities; sluggish or intermittent pulse; hematuresis, epistaxis, ecchymosis, or tarry stool; dark and dull complexion; laboratory examination indicating blood circulation stasis

Diagnostic criteria

2 main symptoms of yin deficiency (or 1 main + 2 secondary symptoms) + 1 main symptom of blood stasis

Blood heat complicated with blood stasis

Add Chinese herbs as Qingrezhixue granules: ComuBuball, Radix arnebiae seu lithospermi

Main symptoms of blood heat

Excessive skin petechiae or bright red bruises located close to each other, anxiety, dry mouth, and thirst

Secondary symptoms of blood heat

Red tongue with yellow moss, strong and rapid pulse, constipation

Symptoms of blood stasis

Red tongue with yellow moss, strong and rapid pulse, constipation

Diagnostic criteria

2 main symptoms of blood heat (or 1 main symptom + 2 secondary symptoms) + 1 main symptom of blood stasis

Wind heat complicated with blood stasis

Add Chinese herbs as Qingrezhixue granules: Lonicera japonica, Fructus Forsythiae, radix platycodonis, mint, bamboo leaf, Schizonepetae, Burdocks

Main symptoms of wind heat

Bright red throat, fever, yellow mucus, small or itchy rash

Secondary symptoms of wind heat

Red tongue with thin yellow or white moss, light and rapid pulse, aversion to wind, cough

Symptoms of blood stasis

Red tongue with thin yellow or white moss, light and rapid pulse, aversion to wind, cough

Diagnostic criteria

2 main symptoms of wind heat (or 1 main symptom + 2 secondary symptoms) + 1 main symptom of blood stasis

Both qi and yin deficiency complicated with blood stasis

Add Chinese herbs as Qingrezhixue granules: Astragalus, Radix pseudostellariae, Glossy Privet Fruit, Eclipta alba, Rhizoma polygonati

Main symptoms of qi deficiency

Weak and easily tired, bad appetite or thin stool, susceptible to cold or diarrhea

Secondary symptoms of qi deficiency

Pale complexion, pale tongue with thin moss or thin and fat tongue with teeth marks, thin and weak pulse

Symptoms of yin deficiency/blood stasis

Pale complexion, pale tongue with thin moss or thin and fat tongue with teeth marks, thin and weak pulse

Diagnostic criteria

2 main symptoms of qi deficiency (or 1 main symptom + 2 secondary symptoms) + 2 main symptoms of yin deficiency (or 1 main symptom + 2 secondary symptoms) + 1 main symptom of blood stasis

Dampness heat complicated with blood stasis

Add Chinese herbs as Qingrezhixue granules: Scutellaria baicalensis, Cogongrass rhizome, Herba pyrrosiae

Main symptoms of dampness heat

Yellow complexion, dark urine or sticky stool, yellow greasy coating on the tongue

Secondary symptoms of dampness heat

Skin sores (e.g., furuncles), bitter taste and bad smell in the mouth, rapid and weak pulse

Symptoms of blood stasis

Skin sores (e.g., furuncles), bitter taste and bad smell in the mouth, rapid and weak pulse

Diagnostic criteria

2 main symptoms of blood heat (or 1 main symptom + 2 secondary symptoms) + 1 main symptom of blood stasis