Measures | Baseline | Post intervention |
---|---|---|
Tumour morphology (off-site) | ||
 - MRI: T1-axial | X | X |
Tumour biomarkers | ||
 - Blood: HIF-1α, TGF-β | X | X |
Anthropometry | ||
 - Height (cm) | X |  |
 - Weight (kg) | X | X |
 - Waist circumference (cm) | X | X |
 - Hip circumference (cm) | X | X |
 - Femoral length (mm) | X |  |
 - Tibial length (mm) | X |  |
 - Body mass index (kg/m2) | X | X |
 - Waist-to-hip ratio | X | X |
Body composition | ||
 - DXA: whole-body, spinal, hip | X | X |
 - pQCT: femoral, tibial | X | X |
Physical assessments | ||
 - NeuroCom Balance Test | X | X |
 - 1RM Strength Test (Leg Extension) | X | X |
 - 400 m Walk Test | X | X |
 - Timed Up and Go Test | X | X |
Other biomarkers (off-site) | ||
 - Blood: P1NP, ALP, CRP, fasting glucose and lipids | X | X |
 - Urine: NTx | X | X |
Questionnaires | ||
 - Demographic and health history | X |  |
 - Concomitant medications | X | X |
 - Health-related quality of Life (SF-36) | X | X |
 - Cancer-specific quality of life (EORTC: QLQ30, BR23) | X | X |
 - Bone Pain (FACIT-BP) | X | X |
 - Brief Symptom Index (BSI-18) | X | X |
 - Insomnia Severity Index (ISI) | X | X |
 - Godin Leisure-time Exercise | X | X |
Exercise programme | ||
 - Clinic exercise record sheet (prescribed vs. actual) | At each exercise session | |
 - Home exercise record sheet (prescribed vs. actual) | At each exercise session | |
 - Pre-session bone pain, muscle soreness and fatigue (VAS) | At each exercise session | |
 - Post-session rating of perceived exertion and tolerance (VAS) | At each exercise session |