The cost-effectiveness and cost-utility of at-home infrared temperature monitoring in reducing the incidence of foot ulcer recurrence in patients with diabetes (DIATEMP): study protocol for a randomized controlled trial

Table 1 Amputation protocol

Amputation site	Alternative region for measurement on the ipsilateral foot	Region(s) for comparison on the contralateral foot
Hallux	MTH 1 or 2nd toe^a	Hallux
2nd toe	3rd toe	2nd toe
3rd toe	2nd or 4th toe^a	3rd toe
Hallux and (trans)metatarsal I	- Most distal plantar part of the amputation site or 2nd toe^a	- Hallux
Hallux and (trans)metatarsal I	- Most distal plantar part of the amputation site	- MTH 1
2nd toe and (trans)metatarsal II	3rd toe	2nd toe
3rd toe and (trans)metatarsal III	- 4th toe	- 3rd toe
3rd toe and (trans)metatarsal III	- Most distal plantar part of the amputation site	- MTH 3
5th toe and (trans)metatarsal V	Most distal plantar part of the amputation site	MTH 5
Transmetatarsal amputation of the forefoot	Most distal plantar part of the amputation site at the base of the 1st, 3rd, and 5th metatarsals	MTH 1, 3, and 5^b
Amputation of the forefoot through the Lisfranc joint	The plantar site of the 1st cuneiform bone, 3rd cuneiform bone, and the cuboid bone	MTH 1, 3, and 5^b
Amputation of the forefoot through the Chopart joint	Most distal plantar part of the amputation site: medial, mid, and lateral	MTH 1, 3, and 5^b

^aBased on temperature values in the first 2 weeks, the investigator chooses the alternative region
^bIn case of a transmetatarsal amputation of the forefoot, or a more proximal amputation, no alternative region to measure for the hallux, 2nd and 3rd toes can be identified. In these cases, the measured temperatures of these regions in the intact foot are compared with the mean temperature of these regions measured in the first 2 weeks of temperature monitoring, using the same foot as reference. This is comparable to the protocol used for participants with a unilateral transtibial amputation. For further explanation, see the text

ISSN: 1745-6215