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Table 1 Management of BP during the first week after randomization

From: Controlling Hypertension After Severe Cerebrovascular Event (CHASE): study protocol for a randomized controlled trial

SBP level

Approaches

Individualized BP-lowering group

Above the rangea

Increase the dose of AHD or use other stronger AHDs

In the rangea

Maintain the regimen

Below the rangea and > 100 mmHg

Reduce the dose of AHD or withdraw AHD

< 100 mmHg

Use vasopressor agents

Guideline-recommended BP lowering-group

> 200 mmHg in AIS

> 180 mmHg in ICH

Increase the dose of AHD or use other stronger AHDs

< 200 and > 100 mmHg in AIS

< 180 and > 100 mmHg in ICH

Use the least dose of AHD to keep SBP not > 200 mmHg in AIS, 180 mmHg in ICH

< 100 mmHg

Use vasopressor agents

  1. a10–15% reduction from admission level and in the range of 130–180 mmHg
  2. AHD antihypertensive drug, AIS Acute ischemic stroke, BP blood pressure, ICH intracerebral hemorrhage, SBP systolic blood pressure