Table 1 Patient, infection, and pathogen characteristics among critically ill patients with bloodstream infection
Characteristica | N (%), Median (IQR) |
|---|---|
Patient characteristic | |
Male sex | 63 (55) |
Age in years | 67 (57–78) |
APACHE II Score | 22 (18–26) |
Baseline vasopressor use | 60 (52) |
Admission category | |
Medical | 78 (68) |
Surgical | 24 (21) |
Trauma | 6 (5) |
Neurological/neurosurgical | 6 (5) |
Burns | 1 (1) |
Comorbidity | |
Coronary artery disease | 23 (20) |
Congestive heart failure | 16 (14) |
Arrhythmia | 15 (13) |
Peripheral vascular disease | 14 (12) |
Diabetes mellitus | 40 (35) |
Renal insufficiency | 13 (11) |
Dialysis dependency | 4 (4) |
Chronic obstructive pulmonary disease | 16 (14) |
Liver disease | 8 (7) |
Obesity | 16 (14) |
Solid malignancy | 18 (16) |
Leukemia/lymphoma | 1 (1) |
Steroids/immunosuppression | 10 (9) |
Infection characteristics | |
Acquisition of bacteremia | |
Community-acquired | 69 (60) |
Hospital-acquired | 19 (17) |
ICU-acquired | 27 (24) |
Source of bacteremia | |
Lung | 31 (27) |
Intra-abdominal/hepato-biliary | 29 (25) |
Urinary tract | 26 (23) |
Vascular-catheter-related | 9 (8) |
Skin and/or soft tissue | 4 (3) |
Other | 4 (3) |
Undefined/unknown | 12 (10) |
Top 10 most commonly isolated pathogens in blood culturesb | |
Escherichia coli | 28 (22) |
Klebsiella spp. | 18 (14) |
Enterococcus spp. | 17 (13) |
Streptococcus pneumoniae | 13 (10) |
Coagulase-negative staphylococci | 12 (9) |
Enterobacter spp. | 6 (5) |
Pseudomonas spp. | 4 (3) |
Serratia spp. | 4 (3) |
Citrobacter spp. | 3 (2) |
Streptococcus anginosus group | 3 (2) |