Table 1 Inclusion and exclusion criteria

Adult patients undergoing elective colorectal surgery

Age < 18 years

Legally incapacitated patients

Patients who are unable to sign informed consent Patients who have an inability to take medication orally

Patients who have undergone abdominal surgery within 30 days before randomization

Patients with a documented allergy to colistin or aminoglycoside antibiotics

Pregnant women or nursing mothers

Patients diagnosed with myasthenia gravis

Patients with a pre-existent stoma

Patients who previously participated in the PreCaution trial or patients who already received study medication but for whom surgery was postponed for more than 7 days