Skip to main content

Table 1 PAGPROS medication titration schedule

From: Pregabalin versus gabapentin in the treatment of sciatica: study protocol for a randomised, double-blind, cross-over trial (PAGPROS)

 

Medication

Total daily dose

Week

Pregabalin

 

 1

1 × 150-mg capsule in the morning

150 mg/day

 2

1 × 150-mg capsule three times daily (middle dose is placebo)

300 mg /day

 3–8

2 × 150-mg capsules three times per day (middle dose is placebo)

600 mg/day

Week

Gabapentin

 

 1

1 × 400-mg capsule in the morning

400 mg/day

 2

1 × 400-mg capsule three times per day

1200 mg/day

 3–8

2 × 400-mg capsules three times per day

2400 mg/day

  1. PAGPROS Pregabalin and Gabapentin Prospective Clinical Trial for the Treatment of Sciatica: A Randomised, Double-Blind, Cross-over Study