Total N (intervention + control) | Ratio | Type 1 error | Proportion of patients achieving a reduction in ICS or OCS | Power | ||
---|---|---|---|---|---|---|
Control | Intervention | Difference | ||||
400 (320 + 80) | 4:1 | 0.05 | 10% | 26% | 16% | 83% |
300 (240 + 60) | 4:1 | 0.05 | 10% | 29% | 19% | 83% |
200 (160 + 40) | 4:1 | 0.05 | 10% | 34% | 24% | 83% |