Fig. 3
From: Association of the FDA Amendment Act with trial registration, publication, and outcome reporting
FDA reviewer trial interpretation and publication, along with published interpretation of the trial findings, for all novel therapeutic agents in cardiovascular disease and diabetes approved by the US Food and Drug Administration (FDA) between 2005 and 2014, characterized based on the number of trials (a) and the number of patients participating in the trials (b). FDA reviewer trial interpretation as positive, equivocal, or negative