Inclusions: | Â |
---|---|
Age | 18–65 |
Education | <16 years or < Bachelor’s degree |
Cigarette frequency | ≥5 cigarettes per day |
Cigarette history | Continuously for at least the last 12Â months |
Cigarette flavor | Willing to smoke one flavor of cigarette (menthol or non-menthol) |
Comprehension | Able to read and write in English and to understand and consent to study procedures |
Smoking cessation | Made no serious quit attempt with/without pharmacotherapy in the prior 1Â month and have no plans to quit in the next 6Â months |
Availability | Accessibility to study centers and to receive phone calls for the next 8Â months |
Exclusions: | Current pregnancy or nursing, unstable or serious medical conditions, prisoners or subject to correctional supervision, systolic blood pressure ≥160 mmHg, use of non-cigarette nicotine delivery product in the past week, difficulty providing blood samples, regular use of illegal drugs, inpatient treatment for substance abuse or mental health condition in past 6 months, alcohol abuse hindering person’s ability to participate, other members of the household currently participating in a trial related to reduced nicotine cigarettes, major surgery planned in the next 8 months (not including outpatient), or any other factor that may affect adherence or pose a health risk to the participant |