Ā | Ā | Study period | ||||
---|---|---|---|---|---|---|
Visit | Screening | Allocation | Intervention period | Vaccination day | Test day | Follow-up |
Time point | Week 0 | Week 4 | Weeks 4ā10 | Week 10 | Week 10 | Week 14 |
Enrolment: | ||||||
āEligibility screen | X | Ā | Ā | Ā | Ā | Ā |
āInformed consent | X | Ā | Ā | Ā | Ā | Ā |
āAllocation | Ā | X | Ā | Ā | Ā | Ā |
Interventions: | ||||||
āIntervention condition | Ā | Ā | X | Ā | Ā | Ā |
āControl condition | Ā | Ā | X | Ā | Ā | Ā |
Assessments: | ||||||
āSerum blood sample | X | Ā | Ā | X | X | X |
āHeparin blood sample | X | Ā | Ā | X | X | Ā |
āMedical screening questionnaire | X | Ā | Ā | Ā | Ā | Ā |
āMINI Psychiatric Interview | X | Ā | Ā | Ā | Ā | Ā |
āIGRA test (interferon-gamma release assay) | X | Ā | Ā | Ā | Ā | Ā |
āHIV test | X | Ā | Ā | Ā | Ā | Ā |
āVaccination | Ā | Ā | Ā | X | Ā | Ā |
āPsychophysiological stress tasks | Ā | Ā | Ā | Ā | X | Ā |
āSaliva samples | X | Ā | Ā | X | X | X |
āHeart rate, heart rate variability and skin conductance levels | X | Ā | Ā | Ā | X | X |
āQuestionnaires | X | Ā | Ā | X | X | X |