Table 1 Summary of study population (THIN database) by practice and patient-level characteristics
Practice characteristics | |
 Number of general practices | 430 |
 General practice sizea, median [IQR] | 241 [150–351] |
Location, N (%) | |
 England | 322 (75) |
 Northern Ireland | 21 (5) |
 Scotland | 56 (13) |
 Wales | 31 (7) |
Patient characteristics | |
 Number of patients | 112,633 |
 Age, median [IQR] | 70 [60–78] |
 Sex (male), N (%) | 61,944 (55) |
Location, N (%) | |
 England | 88,838 (79) |
 Northern Ireland | 3464 (3) |
 Scotland | 12,461 (11) |
 Wales | 7870 (7) |
Deprivation quintiles, N (%) | |
 1 (most affluent) | 23,853 (21) |
 2 | 23,106 (21) |
 3 | 23,031 (20) |
 4 | 22,054 (20) |
 5 (most deprived) | 16,352 (15) |
 Unknown | 4237 (4) |
Clinical measures | |
 HbA1c (%), median [IQR] | 7.05 [6.4–7.9] |
 HbA1c (%), mean (SD) | 7.35 (1.41) |
 Systolic blood pressure (mmHg), mean (SD) | 134 (16) |
 Diastolic blood pressure (mmHg), mean (SD) | 75 (10) |
 BMI (kg/m2), median [IQR] | 29.8 [26.4–34.1] |
 Total cholesterol (mmol/L), median [IQR] | 4.1 [3.5–4.7] |
 HDL cholesterol (mmol/L), median [IQR] | 1.19 [1.00–1.40] |
Medication, N (%) | |
 Insulin | 66,530 (59.1) |
 Other hypoglycaemic medication | 33,061 (29.4) |
Clinical outcomes, N (%) | |
 Atrial fibrillation | 1101 (1.058) |
 Chronic kidney disease | 381 (0.349) |
 Chronic obstructive pulmonary disease | 846 (0.801) |
 Ischaemic heart disease | 967 (1.109) |
 Peripheral vascular disease | 575 (0.545) |
 Stroke | 458 (0.426) |