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Table 3 Dose modification of valaciclovir according to creatinine clearance

From: Valaciclovir to prevent Cytomegalovirus mediated adverse modulation of the immune system in ANCA-associated vasculitis (CANVAS): study protocol for a randomised controlled trial

Creatinine clearance (CrCl ml/min)a

Valaciclovir dose

>75

2 g four times a day

51–75

1.5 g four times a day

26–50

1.5 g three times a day

10–25

1.5 g two times a day

  1. aTests performed within 6 months of the pre-baseline visit can be used for this assessment