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Table 8 Severity of grading and use of normal and abnormal laboratory values

From: TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial

 

Grade 1

Grade 2

Grade 3

Grade 4

Hemoglobin

8.5–10.0 g/dL

7.5–8.4 g/dL

6.5–7.4 g/dL

<6.5 g/dL

Absolute neutrophil count

1000–1300/mm3

750–999/mm3

500–749/mm3

<500/mm3

Platelets

100,000–124,999/mm3

50,000–99,999/mm3

25,000–49,999/mm3

<25,000/mm3

Creatinine

1.1–1.3 × ULN

1.4–1.8 × ULN

1.9–3.4 × ULN

≥3.5 × ULN

Alanine aminotransferase

1.25–2.5 × ULN

2.6–5.0 × ULN

5.1–10.0 × ULN

>10.0 × ULN

  1. ULN upper limit of normal