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Fig. 7 | Trials

Fig. 7

From: Design of trials for interrupting the transmission of endemic pathogens

Fig. 7

Sequence selection. Three hierarchical sequences applied across Rusinga Island for two levels of intervention efficacy, 30 % and 80 %. Results are color coded by the meta-cluster membership. Reading from the left, the meta-cluster sequences are [V, II, VII, III, IV, VIII, I, VI, IX], [V, IV, IX, III, VI, I, VIII, V, II], and [IV, VII, II, IX, III, VIII, I, V, VI]. Coverage intervals widen upon introduction of the intervention to meta-cluster VIII, located at the base of the peninsula in the north-east of the island, in the right two sequences. Coverage intervals were off the scale for the last meta-cluster of sequence 298. Of the three cluster sequences presented, only sequence 296 met the criteria for entry into the pool for the SolarMal randomization sequence selection lottery (coverage intervals of the primary effectiveness measure, ε 5, less than 10 % from time points 60 to 100, and no single village rollout greater than 6 months’ duration)

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