Table 1 PrEvENT inclusion and exclusion criteria

Inclusion criteria

 • Clinically localised prostate cancer

 • Listed for radical prostatectomy

 • Capacity to provide informed consent

 • Aged 18 or over

 • Sufficient understanding of the English language

Exclusion criteria

 • Unable to provide informed consent

 • Unsuitable to participate following guidance from their clinician

 • Unable to undergo follow-up

 • Factors that constrain participation in any aspect of the intervention, including:

  o Co-morbidities, for example:

   ▪ Congestive heart failure or angina, recent myocardial infarction or breathing difficulties requiring oxygen use or hospitalisation

  o Unable to walk without the aid of a mobility aid (other than a walking stick)

  o Religious beliefs

  o Allergy to lycopene

 • Current heavy consumers of the nutritional element of the intervention, that is, taking daily lycopene supplements for more than 3 months

 • Current participation in high levels of regular physical activity, for example doing strenuous activity five or more times a week for long enough to work up a sweat

 • Any additional reason for not being able to participate in any aspect of the intervention