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Fig. 3 | Trials

Fig. 3

From: Comparing half-dose photodynamic therapy with high-density subthreshold micropulse laser treatment in patients with chronic central serous chorioretinopathy (the PLACE trial): study protocol for a randomized controlled trial

Fig. 3

Examples of areas treated in photodynamic therapy and micropulse laser treatment. Examples of imaging features on fluorescein angiography (FA) and indocyanine green angiography (ICG) angiography in chronic central serous chorioretinopathy (cCSC), and the corresponding treatment areas for photodynamic therapy (PDT) and high-density subthreshold micropulse laser treatment (HSML). a-b FA of the right eye of a patient showing hyperfluorescent “hot spots,” indicating leakage inferior of the fovea (a). On ICG angiography, an area of hyperfluorescence, which corresponds to the hyperfluorescent area on the FA, is seen (b). c-f An example of a PDT spot (white circle) overlapping the hyperfluorescent area on the ICG angiography plus 1 mm as described in the protocol (c). HSML treatment scheme that would apply to the same eye, in which only the central foveal area is excluded for treatment (white circle). The hyperfluorescent area on the ICGA is treated with numerous, nonoverlapping adjacent laser spots (white area) (d)

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