Table 2 Inputs used for acute lower respiratory tract infection (ALRI) power calculation

P(ALRI) for controls – all clinical ALRI

0.30

Enwere 2007 (Table 2, column 6, rows 1 and 2)

No ALRI incidence data is available for Ghana; the Enwere data, from Gambia, is the best available analogue. Per the CRA ER, the RR of this exposure level is 2.43

P(ALRI) for BioLite intervention arm

0.20

CRA ER curve

Assuming the CRA ER and an exposure reduction of 60 % (130 μg/m³ → 78 μg/m³), which gives an RR of 1.65

P(ALRI) for LPG intervention arm

0.15

CRA ER curve

Assuming the CRA ER and a residual exposure of 20 μg/m³, which gives an RR of 1.22

95 % plausible interval for P(ALRI) for controls

0.26 – 0.35

Enwere 2007

Estimated from Enwere et al. 2007

Level (α)

0.05

n/a

n/a