Skip to main content

Table 1 Summary of the outcome measures

From: The effects of a protein enriched diet with lean red meat combined with a multi-modal exercise program on muscle and cognitive health and function in older adults: study protocol for a randomised controlled trial

Variables

Data collection method

Data collection points (weeks)

Primary outcome measures

Baseline

Baseline

12

24

36

48

Muscle mass and cross-sectional area

Dual energy X-ray absorptiometry (DXA) total body and regional lean mass

x

 

x

  
 

Peripheral quantitative computed tomography (pQCT) scan at 25% femur site

x

 

x

  

Muscle strength

Leg press

x

 

x

  
 

Isometric knee extensor strength

x

 

x

  

Cognitive function

Cogstate Brief Battery computerized tests

x

x

x

  
 

Behaviour Rating of Inventory of Executive Function-Adult Version (BRIEF-A)

x

 

x

  

Secondary Outcome Measures

 Muscle Function

Four-square step test

x

 

x

  
 

4 meter walk

x

 

x

  
 

30-second sit-to-stand test

x

 

x

  
 

Timed up and go test

x

 

x

  

 Fat mass and inter-/intra-muscular fat

DXA (total body and regional) and pQCT (25% femur site)

x

 

x

  

 Biochemistry and hormonal measures

Overnight fasted blood collection

x

x

x

  

 Neurotrophic markers

Overnight fasted blood collection

x

x

x

  

 Adipokines and Inflammatory markers

Overnight fasted blood collection

x

x

x

  

 Blood lipids

Overnight fasted blood collection

x

x

x

  

 Bone mineral density

DXA total body, hip and spine scan

x

 

x

  

 Blood pressure

Automated measurement

x

 

x

  

 Health related Quality of Life

Short form (SF)-36 version 2 questionnaire

x

 

x

  

 Neural plasticity and voluntary activation

Transcranial Magnetic Stimulation (TMS) *

x

x

x

  

Additional Measures

 Anthropometry

Height, weight and body mass index (BMI)

x

 

x

  

 Health and Lifestyle information

Lifestyle Questionnaire

x

 

x

  

 Habitual physical activity

Community Healthy Activities Model Program for Seniors questionnaire

x

 

x

x

x

 Memory and mood

Memory Assessment Questionnaire (MAC-Q)

x

 

x

  

 Depression and anxiety

The Hospital Anxiety and Depression Scale (HADS) questionnaire

x

 

x

  

 Diet

24-hour food diaries

Monthly

x

x

 Compliance to red meat and carbohydrates

Food records

Daily calendar

  

 Vitamin D supplement compliance

Pill count

  

x

  

 Compliance to exercise program

Exercise cards

Monthly

  

 Adverse events

Exercise cards and adverse events form

Monthly

  
  1. * TMS will also be assessed at week 4 and 8