Variables | Measurement level that may be consider as adverse events |
---|---|
Haemoglobin | Fall of > 20 g/l from baseline is significant |
Reticulocytes | 10–100 x 109 fall < 10 × 109 is significant |
Lactate dehydrogenase | Increase of > 1.5 x from baseline is significant. |
Bilirubin | Increase of > 1.5 x from baseline is significant |
Creatinine | Increase of > 1.5 from baseline is significant |
Erythropoeitin | Fall of > 50 % from baseline is significant |
Oximetry | Decrease in baseline oximetry of > 3 % from baseline |