Inclusion criteria: |
Age ≥ 18 years |
TIA, amaurosis fugax or minor ischemic stroke (mRS ≤ 3) |
Symptom onset < 6 months |
Impaired glucose tolerance (2-hour post-load glucose level between 7.8 and 11.0 mmol/L) in 2 consecutive measurements |
Exclusion criteria: |
Diabetes mellitus |
History of diabetic ketoacidosis |
Symptoms of type 1 diabetes |
Signs of renal impairment (creatinine of 135 μmol/L or higher for men, and 110 μmol/L or higher for women) |
Known liver disease or disturbed liver function tests (alanine amino transferase, aspartate amino transferase, alkaline phosphatase, or γ-glutamyl transferase increased to more than twice the upper limit of typical values) |
History of lactic acidosis |
Heart failure requiring pharmacological therapy |
Pancreatitis |
Chronic hypoxic lung disease stages III–IV |
Digoxin use |
Pregnancy or breastfeeding |