Inclusion criteria | |
1 | Patients have definite outpatient pathologic diagnosis of breast cancer |
2 | Eligible patients had completed chemotherapy and/or radiotherapy at least 1 month and mastectomy within 5 years |
3 | Stage I to III breast cancer with no evidence of recurrence and metastasis |
4 | Eastern Cooperative Oncology Group Performance Status 0 to 2 |
5 | Traditional Chinese Medicine (TCM) syndrome is differentiated as liver depression and spleen deficiency |
6 | Anticipated survival time exceeds 6 months |
7 | Eligible patients have no plan to receive chemotherapy and/or radiotherapy during the study |
8 | Revised Piper Fatigue Scale score ≥ 4 |
9 | Provided signed informed consent before enrollment |
Exclusion criteria | |
1 | Complicated by serious diseases of heart, liver and kidney, immune and hematopoietic systems |
2 | Children and pregnancy |
3 | Receiving active treatment for anemia with erythropoietin or blood transfusions |
4 | Using steroids to cure cancer-related fatigue |
5 | Diagnosed with depression, mental disease or cognitive impairment |
6 | Allergic to a Chinese herbal compound |