Skip to main content

Table 3 Cytochrome p-450 inhibitors and inducers

From: Pulsed oral sirolimus in advanced autosomal-dominant polycystic kidney disease (Vienna RAP Study): study protocol for a randomized controlled trial

CYP3A4 inhibitors: CYP3A4 inducers
• Bromocriptine • Carbamazepine
• Cimetidine • Rifabutin
• Clarithromycin • Rifampicin
• Danazol • Phenobarbital
• Fluconazole • Phenytoin
• Itraconazole • St John’s Wort (Hypericum perforatum)
• Protease inhibitors  
• Telithromycin  
  1. To avoid potential intoxication or reduced efficacy by accidental co-administration of these substances, every participant will be handed a list of the medication above for emergency use.