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Table 1 Summary of previous trials of remote ischaemic preconditioning (RIPC) in major vascular surgery

From: Preconditioning Shields Against Vascular Events in Surgery (SAVES), a multicentre feasibility trial of preconditioning against adverse events in major vascular surgery: study protocol for a randomised control trial

Trial reference

Number randomised

Operation type

Main findings

Ali et al. Circulation [9]

82

Elective open AAA repair

RIPC produced significant reductions in post-operative troponin levels, myocardial infarctions and serum creatinine levels

Walsh et al. Vasc Endovasc Surgery [10]

40

Elective open AAA repair

RIPC had no significant effect on post-operative renal injury biomarkers.

Walsh et al. J Endovasc Ther [11]

40

Elective EVAR

RIPC produced significant reductions in post-operative biomarkers of renal injury

Walsh et al. Vasc Endovasc Surgery [12]

70

Elective carotid endarterectomy

RIPC had no significant effect on saccadic latency deteriorations or biomarkers of cardiac injury

Li et al. Anesthesiology [13]

62

Elective open AAA repair

RIPC produced significant reductions in biomarkers of intestinal and pulmonary injury

  1. Legend: Table summarising previous trials of remote ischaemic preconditioning in major vascular surgery.
  2. AAA – abdominal aortic aneurysm; EVAR – endovascular aneurysm repair; RIPC – remote ischaemic preconditioning.