Fibromyalgia, milnacipran and experimental pain modulation: study protocol for a double blind randomized controlled trial

Table 1 Summary of evaluation for a patient

Study visit	Visit 1	Phone call	Visit 2
	Day 0	Day 0 + 7 days, 14 days, 21 days (interval 1 day)	Day 28
*Clinical interviews*
Informed consent	×
Inclusion and exclusion criteria	×
Clinical examination: diagnosis of fibromyalgia	×
*Measures*
Numeric pain rating scale	×		×
Assessment of pain threshold to a thermal stimulus	×		×
Test-stimulus intensity ‘pain 60/stimulus’	×		×
Conditioned pain modulation test	×		×
Cantab® tests	×		×
*Treatment*
Randomization: delivery of therapeutic units	×
Reporting of adverse events and concomitant treatments	×	×	×
Treatment compliance		×	×
Reporting of adverse events and concomitant treatments	×	×	×
Return of therapeutic units			×

ISSN: 1745-6215