Figure 1From: Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trialOverview of systematic review of methotrexate use in osteoarthritis. Databases: PubMed, MEDLINE and Embase. Search terms: MeSH headings #1 ‘osteoarthritis’ and #2 ‘methotrexate’. Limits: Humans.Back to article page