- Paper Report
- Open Access
Preinfarction angina protects against in-hospital adverse outcomes in the elderly
- Joanna Lyford1
© Biomed Central Ltd 2001
- Received: 7 March 2001
- Published: 18 October 2001
- Myocardial infarction, preinfarction angina, unstable angina
It is thought that angina experienced by elderly patients prior to a myocardial infarction (MI) may confer some benefits such as a lower incidence of adverse outcomes. This study aims to investigate the nature of the benefits of pre-infarction angina.
Elderly patients with a history of prodromal angina were at a lower risk of experiencing in-hospital death, the combined end point of death and heart failure (6% versus 20.4%, P = 0.02; 10% versus 23.7%, P = 0.07) than those who didn't have angina. The absence of preinfarction angina increased the risk of depressed left ventricular function (ejection fraction <40%), which was observed in 44.8% of those who hadn't experienced angina compared with 26% of those who did. In addition, the angina free group experienced a greater incidence of arrhythmia (complete heart block and ventricular fibrillation) than those who had angina (16.1% versus 4%).
A total of 290 consecutive elderly (>64 years old, n = 143) and adult (<65 years old, n = 147) patients were examined following their first MI.