- Paper Report
- Open Access
Amiodarone as a first choice drug
- Niall Mulvahill1
© Biomed Central Ltd 2001
- Received: 22 September 2000
- Published: 17 October 2001
- Chronic atrial fibrillayion, class III drugs, medical cardioversion
This paper describes a prospective randomised controlled study to assess the effectiveness of amiodarone in converting both short-term and long-lasting atrial fibrillation (AF) after 30 days of treatment.
This research was undertaken because of conflicting reports on the effectiveness (16%-19%) of amiodarone in the conversion of A F. This study also mandated that amiodarone was used as first line drug treatment.
Overall, 80.5% of the amiodarone group and 40% of the placebo group converted to sinus rhythm at 30 days
Patients received intravenous (24 h) followed by oral amiodarone or placebo. All patients received digoxin for the first 24 h. .