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Table 1 Effect of conjugated estrogen and transdermal nitroglycerin on BMD in ovariectomized rats 25.

From: The effects of organic nitrates on osteoporosis: a randomized controlled trial [ISRCTN94484747]

Treatment group, n = 5 for all groups

Percent increase in BMD (L2-L4) over 6 weeks

Sham operated

25% ± 2%

Ovariectomized rats

8% ± 3%

Ovariectomized + estrogen

27% ± 5%*

Ovariectomized + transdermal nitroglycerin

20% ± 3%†

Ovariectomized + estrogen + nitroglycerin

22% ± 2%*

  1. *Different than ovariectomized rats at p < 0.005
  2. † Different than ovariectomized rats at p < 0.02