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Table 2 Efficacy assessment by category of multiple symptom combinations

From: Use of comparative effectiveness research for similar Chinese patent medicine for angina pectoris of coronary heart disease: a new approach based on patient-important outcomes

Multiple symptom combinations

Four groups of patients categorized using the efficacy assessment tool

Group 1

Group 2

Group 3

Group 4

Combination (1 + 2)

(AB1 + AB2)/2 N

(A1 + A2)/2 N

(B1 + B2)/2 N

(ab1 + ab2)/2 N

Combination (1 + 3)

(AB1 + AB3)/2 N

(A1 + A3)/2 N

(B1 + B3)/2 N

(ab1 + ab3)/2 N

Combination (1 + 4)

(AB1 + AB4)/2 N

(A1 + A4)/2 N

(B1 + B4)/2 N

(ab1 + ab4)/2 N

Combination (2 + 3)

(AB2 + AB3)/2 N

(A2 + A3)/2 N

(B2 + B3)/2 N

(ab2 + ab3)/2 N

Combination (2 + 4)

(AB2 + AB4)/2 N

(A2 + A4)/2 N

(B2 + B4)/2 N

(ab2 + ab4)/2 N

Combination (3 + 4)

(AB3 + AB4)/2 N

(A3 + A4)/2 N

(B3 + B4)/2 N

(ab3 + ab4)/2 N

Combination (1 + 2 + 3)

(AB1 + AB2 + AB3)/3 N

(A1 + A2 + A3)/3 N

(B1 + B2 + B3)/3 N

(ab1 + ab2 + ab3)/3 N

Combination (1 + 2 + 4)

(AB1 + AB2 + AB4)/3 N

(A1 + A2 + A4)/3 N

(B1 + B2 + B4)/3 N

(ab1 + ab2 + ab4)/2 N

Combination (1 + 3 + 4)

(AB1 + AB3 + AB4)/3 N

(A1 + A3 + A4)/3 N

(B1 + B3 + B4)/3 N

(ab1 + ab3 + ab4)/3 N

Combination (2 + 3 + 4)

(AB2 + AB3 + AB4)/3 N

(A2 + A3 + A4)/3 N

(B2 + B3 + B4)/3 N

(ab2 + ab3 + ab4)/3 N

Combination (1 + 2 + 3 + 4)

(AB1 + AB2 + AB3 + AB4)/4 N

(A1 + A2 + A3 + A4)/4 N

(B1 + B2 + B3 + B4)/4 N

(ab1 + ab2 + ab3 + ab4)/4 N