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Table 1 Five hypothetical historical vaccine trials

From: A Bayesian prediction model between a biomarker and the clinical endpoint for dichotomous variables

  N Number of infection cases Number of disease cases Vaccine efficiency(95% CI) on disease
Vaccine Placebo Vaccine Placebo
1 2954 2 213 0 23 100.0%(82.5%,100.0%)
2 3200 10 86 1 6 83.3%(-37.6%,99.6%)
3 529 2 45 0 2 100.0%(-431.4%,100%)
4 3674 27 130 3 8 62.7%(-55.5%,93.6%)
5 3452 24 296 0 30 100.0%(87.1%,100.0%)
  1. CI: credible interval.