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Table 1 Five hypothetical historical vaccine trials

From: A Bayesian prediction model between a biomarker and the clinical endpoint for dichotomous variables

 

N

Number of infection cases

Number of disease cases

Vaccine efficiency(95% CI) on disease

Vaccine

Placebo

Vaccine

Placebo

1

2954

2

213

0

23

100.0%(82.5%,100.0%)

2

3200

10

86

1

6

83.3%(-37.6%,99.6%)

3

529

2

45

0

2

100.0%(-431.4%,100%)

4

3674

27

130

3

8

62.7%(-55.5%,93.6%)

5

3452

24

296

0

30

100.0%(87.1%,100.0%)

  1. CI: credible interval.