| Placebo n = 3 | PGE1n = 4 |
---|---|---|
Primary diagnosis (n) | Â | Â |
 Idiopathic | 2 | 0 |
 Aspiration syndrome | 1 | 4 |
Age at start of INO (hours) mean, (SD) | 26.6 (2.1)a | 7.9 (9.4) |
Duration of INO before study aerosol (hours) mean, (SD) | 8.0 (6.0)a | 13.4 (7.2) |
Interval between first OI ≥15 and study aerosol (hours) mean, (SD) | 4.2 (1.2) | 12.2 (5.6) |
Interval between first and second qualifying blood gases (hours) mean, (SD) | 2.4 (1.2) | 4.7 (3.0) |
Interval from randomization to study gas initiation (hours) mean, (SD) | 1.2 (0.08) | 2.3 (0.5) |
Age at randomization (hours) mean, (SD) | 41.7 (15.4) | 19.0 (8.2) |
OI on baseline ABG mean, (SD) | 26.0 (9.5) | 23.8 (17.3) |
Therapies prior to randomization (n): | Â | Â |
 Volume support | 3 | 4 |
 Vasopressor support | 3 | 3 |
 Sedation or analgesia | 3 | 4 |
 Neuromuscular blockade | 2 | 3 |
 Alkalosis | 2 | 1 |
 Surfactant | 3 | 2 |