1) Primary

Intervention improved outcome from baseline to 7 days

Adherence% (>80%) [binary]
 
Diopter

Diopter reduced or increased after treatment

Diopter [continuous]

ttest (ranksum test) or repeated measurement

2) Secondary

Intervention improved outcome from baseline to 7 days

Adherence% (>80%) [binary]
 
Visual acuity

Visual acuity did not increase or decrease after treatment

Visual acuity changes [continuous]

ttest (ranksum test) or repeated measurement

Axial length

Axial length was not increased

Axial length changes [continuous]

ttest (ranksum test) or repeated measurement

Lens thickness

Lens thickness was not increased

Lens thickness changes [continuous]

ttest (ranksum test) or repeated measurement

Ciliary body thickness

Ciliary body thickness was not increased

Ciliary body thickness changes [continuous]

ttest (ranksum test) or repeated measurement

Eye symptoms and systemic symptoms

No adverse symptoms

No adverse symptoms

Chisquared test or Fisher’s exact test

Compliance

Compliance

Cure rate [binary]

Chisquared test or Fisher’s exact test

Combination therapy/treatment

Improvement occurred

Whether other drugs were used during treatment [binary]

Chisquared test or Fisher’s exact test

Adverse event

Improvement occurred

Presence of drugrelated adverse event [binary]

Chisquared test or Fisher’s exact test

3) Baseline analyses:
 
Adherence% (>80%) [continuous]
 
Age
 
CRF [continuous]

ttest (ranksum test)

Weight and height
 
CRF [continuous]

ttest (ranksum test)

Female versus male
 
CRF [binary]

Chisquared test or Fisher’s exact test

Race
 
CRF [more categories]

Chisquared test or ranksum test

Birth weight
 
CRF [continuous]

ttest (ranksum test)

Preterm children
 
CRF [binary]

Chisquared test or Fisher’s exact test

Parental myopia or not
 
CRF [binary]

Chisquared test or Fisher’s exact test

Sibling myopia or not
 
CRF [binary]

Chisquared test or Fisher’s exact test

Daily close reading time
 
CRF [continuous]

ttest (ranksum test)

Outdoor time
 
CRF [continuous]

ttest (ranksum test)

Eye exercises every day or not
 
CRF [binary]

Chisquared test or Fisher’s exact test

Daily sleep time
 
CRF [continuous]

ttest (ranksum test)

Room light conditions
 
CRF [binary]

Chisquared test or Fisher’s exact test

Poor reading habits
 
CRF [more categories]

Chisquared test or ranksum test
