Cord pilot trial - immediate versus deferred cord clamping for very preterm birth (before 32 weeks gestation): study protocol for a randomized controlled trial

Table 1 Immediate versus deferred cord clamping for preterm births: effects for infants

Outcome	Number of trials	Number of participants	Risk ratio	95%confidence interval
Death	13	668	0.63	0.31 to 1.28
intraventricular haemorrhage
any (grade 1 to 4))	10	539	0.59	0.41 to 0.85
severe (grade 3 or 4)	6	305	0.68	0.23 to 1.96
periventricular leukomalacia	2	71	1.02	-0.52 to 5.56
temperature on SCBU admission (°C)^a	3	143	0.14^a	-0.03 to 0.31^a
Transfusion
for anaemia	7	392	0.61	0.46 to 0.81
for hypotension	4	130	0.52	0.24 to 1.11
number of transfusions^a	5	210	-1.26^a	-1.87 to −0.64^a
mean arterial pressure^a
at birth	2	97	3.52^a	0.60 to 6.45^a
at 4 hours	2	111	2.49^a	0.26 to 4.72^a
inotropes for low blood pressure	4	158	0.42	0.23 to 0.77
necrotising enterocolitis	5	241	0.62	0.43 to 0.90
serum bilirubin peak^a	7	320	15.01^a	5.62 to 24.40^a
jaundice requiring phototherapy	3	180	1.21	0.94 to 1.55
oxygen supplementation at 36 weeks	5	209	0.69	0.42 to 1.13

ISSN: 1745-6215