Secondary identifying numbers | ACTRN12613001130752 |
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Source(s) of monetary or material support | |
Primary sponsor | St Vincent’s Hospital, Sydney |
Secondary sponsor(s) | |
Contact for public queries | AW, GA |
Contact for scientific queries | AW, GA |
Public title | Cognitive Bias Modification (CBM) and Obsessive Compulsive Beliefs |
Scientific title | Randomized controlled trial comparing Internet-based cognitive bias modification (active version) for obsessive compulsive disorder versus Internet based cognitive bias modification (control version) on negative interpretation bias. |
Countries of recruitment | Australia |
Health condition(s) or problem(s) studied | Obsessive Compulsive Disorder |
Intervention(s) | Experimental: CBM Version A (Active treatment) |
CBM Version A is an Internet-based intervention taking place over 1 week. | |
Placebo Comparator: CBM Version B (Control) | |
CBM Version B (Control) is an Internet-based intervention taking place over 1 week (identical to CBM Version A without the putative active components). | |
Key inclusion and exclusion criteria | Inclusion: 18 to 65 years of age; Meet Diagnostic and Statistical Manual of the American Psychiatric Association - 4th edition (DSM-IV) criteria for current or lifetime Obsessive Compulsive Disorder; Internet and printer access; Australian resident; fluent in written and spoken English |
Exclusion: Current substance abuse/dependence; Psychotic mental illness (Bipolar or Schizophrenia); change in medication or psychological treatment during last 1 month or intended change during study duration; use of Benzodiazepines, severe depression (PHQ9 > 23), Suicidal (PHQ9 item 9 > 2) | |
Study type | Interventional |
Date of first enrollment | 24 October 2013 |
Target sample size | 70 |
Recruitment status | Recruiting |
Primary outcome(s) | Change in: Interpretations bias (the Ambiguous Scenarios Test for OCD; AST-OCD), the Word Sentence Association Test for OCD (WSAO), and the OC Bias measure. |
Key secondary outcomes | Change in: The Obsessive Beliefs Questionnaire-TRIP (OBQ-TRIP), the Patient Health Questionnaire (PHQ-9); the Dimensional Obsessive-Compulsive Scale (DOCS). Change in diagnostic status will be indexed using the OCD M.I.N.I Module at baseline and follow up. |