Baseline | Interim assessment -six weeks | Three months | Follow up -six months | |
---|---|---|---|---|
Informed consent | X | |||
Inclusion and exclusion criteria | X | |||
Demographic data | X | |||
Medical and surgical history | X | |||
Adverse effects | X | X | X | |
Current daily treatment | X | X | X | X |
Dental status | X | X | X | X |
Routine dental visit | X | |||
Physical examination | X | X | X | X |
Blood test (CBC, hs-CRP, serum calcium, serum creatinine, ESR, vitamin D, PTH, CTX, osteocalcin) | X | X | X | X |
Pain on 100 mm VAS | X | X | X | X |
EIFEL score | X | X | X | X |
FABQ score | X | X | X | X |
Dallas score | X | X | X | X |
MacTar score | X | X | X | X |
MCII/PASS score | X | X | X | |
Finger-to-floor distance | X | X | X | X |
Schober’s test | X | X | X | X |
Number of nightly awakenings | X | X | X | X |
Severity of MS (100 mm VAS) | X | X | X | X |
Duration of MS (min) | X | X | X | X |