Table 4 Changes in the main clinical and biological parameters between month 0 and month 24
Variable | Group | Month 0 Mean (SD) | Month 24 Mean (SD) | Estimated change over 24Â months (SE) | Estimated difference ( P-value) |
|---|---|---|---|---|---|
Systolic blood pressure (mmHg) | Intervention (n = 905) | 145.9 (15.3) | 139.6 (14.6) | -6.00 (0.46) | -4.76 (< 0.001) |
Usual care (n = 927) | 138.7 (13.5) | 137.2 (12.6) | -1.24 (0.48) | ||
Diastolic blood pressure (mmHg) | Intervention (n = 905) | 83.7 (11.7) | 80.2 (10.4) | -3.32 (0.38) | -1.88 (< 0.001) |
Usual care (n = 927) | 80.6 (9.2) | 79.2 (8.0) | -1.44 (0.38) | ||
LDL cholesterol (mmol/L) | Intervention (n = 905) | 3.18 (1.03) | 2.82 (0.85) | -0.31 (0.03) | 0.05 (0.075) |
Usual care (n = 927) | 3.21 (1.03) | 2.92 (0.91) | -0.26 (0.03) | ||
MDRD-estimated GFR (ml/min) | Intervention (n = 905) | 79.6 (19.6) | 80.6 (20.1) | 1.52 (0.48) | 2.72 (< 0.001) |
Usual care (n = 927) | 80.8 (20.2) | 78.9 (20.5) | -1.20 (0.48) | ||
Framingham-Anderson Score (%) | Intervention (n = 905) | 17.47 | 15.24 | -2.23 | 0.06 (0.001) |
Usual care (n = 927) | 17.00 | 15.81 | -1.19 | ||
Weight (kg) | Intervention (n = 905) | 85.8 (16.5) | 85.5 (16.8) | -0.28 (0.12) | -0.12 (0.470) |
Usual care (n = 927) | 85.6 (15.9) | 85.4 (16.1) | -0.16 (0.12) | ||
Waist circumference (cm) | Intervention (n = 905) | 105.1 (12.8) | 104.9 (13.3) | -0.08 (0.16) | -0.24 (0.269) |
Usual care (n = 927) | 105.1 (13.3) | 105.3 (13.8) | 0.16 (0.16) | ||
HbA1c (%) | Intervention (n = 527) | 7.01 (1.12) | 7.03 (1.10) | 0.03 (0.04) | 0.01 (0.341) |
|  | Usual care (n = 521) | 7.01 (1.23) | 7.03 (1.13) | 0.02 (0.04) |  |